Suggested Diagnostic Evaluation for NORSE and FIRES (Updated 2020)

Summary:

This downloadable checklist outlines suggested diagnostic investigations for suspected cases of New Onset Refractory Status Epilepticus (NORSE) and Febrile Infection-Related Epilepsy Syndrome (FIRES). It is intended as a helpful clinical tool—not an exhaustive or prescriptive list.

The guideline was developed by the NORSE Institute’s Medical Advisory Board with contributions from experts including Drs. Nicolas Gaspard, Claudine Sculier, Lawrence J. Hirsch, Sara Hocker, Zubeda Sheikh, Shivani Ghoshal, and Yashwanth Pulluru.

Health professionals are encouraged to use this as a reference and adapt based on each individual case. Additions or suggestions can be submitted through the NORSE Institute’s Contact page.

Download the checklist (PDF):

NORSE Diagnostic Evaluation – Updated Sept 2020

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International Treatment Recommendations for NORSE and FIRES (Epilepsia, 2022)