Sample Treatment Algorithm: Generalised Convulsive Status Epilepticus

This resource provides a sample treatment algorithm for managing generalised convulsive status epilepticus (GCSE) in both adults and children. It is intended as a clinical reference for healthcare professionals who care for patients with an active or working diagnosis of status epilepticus.

The goal of therapy is to terminate both clinical and electrical seizure activity safely and promptly, reducing the risk of mortality and long-term morbidity.

This pathway outlines stepwise treatment recommendations, helping clinicians act quickly and decisively during what are often fast-moving and high-risk situations.

Download the Guideline

You can view or download the full algorithm here: Status Epilepticus Treatment Guideline (PDF) Published: October 2020

About This Resource

This treatment pathway has been shared with permission from:

●       Abdalla Ammar, PharmD

●       Lawrence J. Hirsch, MD

●       Emily J. Gilmore, MD

●       Yale New Haven Hospital Department of Pharmacy Services

●       Yale University Department of Neurology

We are grateful to the team for making this information publicly available for the benefit of the wider neurocritical care community.

Please note: This is a sample guideline only. It may not reflect the most up-to-date protocols or be appropriate for all clinical settings. Clinical judgement and local policies should always guide final treatment decisions.